Regular price: $20.99

Membership details Membership details
  • A 30-day trial plus your first audiobook, free.
  • 1 credit/month after trial – good for any book, any price.
  • Easy exchanges – swap any book you don’t love.
  • Keep your audiobooks, even if you cancel.
  • After your trial, Audible is just $14.95/month.
Select or Add a new payment method

Buy Now with 1 Credit

By confirming your purchase, you agree to Audible's Conditions of Use and Amazon's Privacy Notice. Taxes where applicable.

Buy Now for $20.99

Pay using card ending in
By confirming your purchase, you agree to Audible's Conditions of Use and Amazon's Privacy Notice. Taxes where applicable.

Add to Library for $0.00

By confirming your purchase, you agree to Audible's Conditions of Use and Amazon's Privacy Notice. Taxes where applicable.

Publisher's Summary

For 200 years, a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass. What these strange conditions, including fatal familial insomnia, kuru, scrapie, and mad cow disease, share is their cause: prions. Prions are ordinary proteins that sometimes "go wrong", resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA. And the diseases they bring are now spreading around the world.
In The Family That Couldn't Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion's hidden past and deadly future. Through exclusive interviews and original archival research, Max explains this story's connection to human greed and ambition, from the Prussian chemist Justus von Liebig, who made cattle meatier by feeding them the flesh of other cows, to New Guinean natives whose custom of eating the brains of the dead nearly wiped them out.
The biologists who have investigated these afflictions are just as extraordinary. They include Daniel Carleton Gajdusek, a self-described "pedagogic pedophiliac pediatrician" who cracked kuru and won the Nobel Prize, and another Nobel winner, Stanley Prusiner, a driven, feared self-promoter who identified the key protein that revolutionized prion study.
©2006 D.T. Max (P)2006 Tantor Media, Inc.
Show More Show Less

Critic Reviews

"Very timely and compellingly written." (Booklist)
Show More Show Less

Customer Reviews

Most Helpful
5 out of 5 stars
By David on 11-04-06

A great scientific mystery

This has become one of my favorite non-fiction books on audible. If you enjoyed "Splendid Solution", "The Great Influenza" or "Germs" you will love this one. It may not have the humor or entertainment value of "The Omnivore's Delimma" but the author does a fine job of weaving personal stories with science to create a fascinating story. This is a great introduction to Mad Cow and other prion diseases, and also provides a distrubing account of how governments bumble their way through such outbreaks.

Grover Gardner also performs another excellent reading. In my opinion, Gardner is by far the top narrator for any material that has any scientific or technical content. His voice moves gracefully over the text - always with the right nuance and pronunciation - allowing the listener to become quite captivated by the story.

Read More Hide me

15 of 16 people found this review helpful

5 out of 5 stars
By Maria on 03-24-10

Very entertaining and enlightening

Wonderfully written account of prions: the diseases associated with them; the nobel laureates who study them; people affected; and how the problem began, was discovered, and has spread. Like a PBS special and a novel rolled into one, you learn quite a bit while being thoroughly entertained. A page turner.

Read More Hide me

5 of 5 people found this review helpful

See all Reviews