The Biology of Desire

  • by Marc Lewis, PhD
  • Narrated by Don Hagen
  • 7 hrs and 40 mins
  • Unabridged Audiobook

Publisher's Summary

Through the vivid, true stories of five people who journeyed into and out of addiction, a renowned neuroscientist explains why the "disease model" of addiction is wrong and illuminates the path to recovery. The psychiatric establishment and rehab industry in the Western world have branded addiction a brain disease based on evidence that brains change with drug use. But in The Biology of Desire, cognitive neuroscientist and former addict Marc Lewis makes a convincing case that addiction is not a disease and shows why the disease model has become an obstacle to healing. Lewis reveals addiction as an unintended consequence of the brain doing what it's supposed to do - seek pleasure and relief - in a world that's not cooperating. Brains are designed to restructure themselves with normal learning and development, but this process is accelerated in addiction when highly attractive rewards are pursued repeatedly. Lewis shows why treatment based on the disease model so often fails and how treatment can be retooled to achieve lasting recovery, given the realities of brain plasticity. Combining intimate human stories with clearly rendered scientific explanation, The Biology of Desire is enlightening and optimistic listening for anyone who has wrestled with addiction either personally or professionally.


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Customer Reviews

Most Helpful

Should be the neuroanatomy of desire

The information stimulated my striatum, traveled to my orbitofrontal complex, fermented in my prefrontal complex, then took the long voyage via the stercorotaural pathways to my celiac plexus, initiating a migrating motor complex. Then the author presented his opinions on addiction.
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- Brandon

Interesting concept good narration

Neuroscientist and former addict Marc Lewis writes an engaging study of the biological changes that occur in an addicted brain, complete with personal stories about himself and several addicts that he interviewed. Lewis points out that there are two major models for addiction - the disease model and the choice model - and argues why he believes the disease model has outlived its use and is now harming rather than helping addicts.

The disease model of addiction is highly accepted by clinicians, psychologists, and insurance companies right now. It posits that the more an addict uses a substance, the more his brain changes, and the more he needs the drug. Furthermore, some people have a biological preinclination for addiction - it doesn't mean that they will become addicts, but the genetic preinclination raises their chance of becoming an addict under the right environmental stimulus. The combination of genetic factors and changes in the brain suggest to clinicians that addiction is a disease. A lot of money, therapy, and medication currently goes into treating addiction as a disease - often successfully.

Lewis argues, though, that changes in the brain and genetic preinclination do-not-a-disease-make. After all, every experience changes your brain - and some events, like falling in love, change your brain in much the same way addiction changes it. Furthermore, much as people have a preinclination for addiction, they also have a preinclination to temperament. For instance, an introverted, agreeable parent is more likely to have an introverted, agreeable child. Despite this heritability, temperament is not considered a disease. So why do we pick-and-choose which heritable brain-changing habits are a disease?

My answer is that addiction is considered a disease whereas in-love and temperament are not considered diseases because in-love and temperament do not generally cause clinically significant impairment in an individual's ability to function in the workplace and social interactions. And when they do inhibit the individual's ability to function, then they are considered a disease.

Instead of the disease model, Lewis supports the "choice" model. People choose to abuse substances in the first place, and continue to make that choice. And when they give up the substance abuse, it is generally because they have chosen that now is the right time to give it up.

Lewis spends the great part of this book describing why he feels viewing addiction as a disease is harmful to addicts as well as unhelpful for treatment. When an addict views his problem as a disease, then he might feel helpless to make his situation better. Whereas if he views it as a choice, he recognizes that he has power over this problem. You might notice that this is in stark contrast to the first step of AA in which the addict accepts that he is powerless over his addiction. In fact, in the stories of Lewis' interviewees, none of them mentioned AA or NA as a helpful tool for stopping their addiction.

Lewis also points out that although medication and therapy generally help the individual to give up alcohol to begin with, there is a very high relapse rate. And that is because although the individual doesn't want the negative effects of his addiction, he has not yet accepted the choice to give up the drug.

Lewis claims that many people view the choice model and the disease model as mutually exclusive, but he believes that they are not. I would tend to agree with him on this. I don't see the harm in viewing addiction as a disease - in fact, I think this model would be very helpful to a certain subset of addicts - it provides them a reason to say "this is not my fault, I have a disease, and I need to live as healthy a life as I can in order to not let it ruin my life." But I also think the choice model is helpful to another subset of addicts - it provides them the ability to say "I have the power to choose not to use. I am not powerless."
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- Rachel "I read all sorts of books from various non-fiction to YA fantasy. Love them all!"

Book Details

  • Release Date: 07-21-2015
  • Publisher: Gildan Media, LLC