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Publisher's Summary

It's not fiction: Gary Lynch is the real thing, the epitome of the rebel scientist - malnourished, contentious, inspiring, explosive, remarkably ambitious, consistently brilliant. He is one of the foremost figures of contemporary neuroscience, and his decades-long quest to understand the inner workings of the brain's memory machine has begun to pay off.
Award-winning journalist Terry McDermott spent nearly two years observing Lynch at work and now gives us a fascinating and dramatic account of daily life in Lynch's lab - the highs and lows, the drudgery and eureka moments, the agonizing failures. He provides detailed, lucid explanations of the cutting-edge science that enabled Lynch to reveal the inner workings of the molecular machine that manufactures memory. And he explains where Lynch's sights are now set: on drugs that could fix that machine when it breaks, drugs that would enhance brain function during the memory process and that hold out the possibility of cures for a wide range of neurological conditions, including Alzheimer's, Parkinson's, and Attention Deficit Hyperactivity Disorder (ADHD). Here is an essential story of science, scientists, and scientific achievement - galvanizing in the telling and thrilling in its far-reaching implications.
©2010 Terry McDermott (P)2010 Tantor
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Critic Reviews

"[McDermott's] exposition of the science is lucid, and his first-hand account of Lynch's seething laboratory is riveting, full of prickly egos, desperate battles for grants, and epic experiments...that become daily roller-coasters of triumph and despair as results trickle in. This is an engrossing story of science and the brilliant, flawed people who make it." (Publishers Weekly)
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Customer Reviews

Most Helpful
5 out of 5 stars
By Joe on 04-18-10

Fascinating tale of a scientific maverick's lab

Disclaimer: I am a psychological scientist, so your enjoyment mileage may differ, but I found 101 Theory Drive a truly fascinating tale. McDermott's detailed account of the scientific (and personal) life of Gary Lynch--who first correctly worked out the neurological bases of memory formation in the brain--is full of interesting details about the life and work of a brilliant thinker and scientific investigator...warts, setbacks and all. It's got a lot of physiological detail, which may bore/confuse some readers, but it does not require a lot of knowledge to follow, and it is truly fascinating if you are at all interested in how the brain becomes "mind". I highly recommend this book for anyone interested in the way science REALLY works and in how creative thinkers often work.

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14 of 14 people found this review helpful

4 out of 5 stars
By Roy on 08-23-10

Entertaining and Informative

In this book Terry McDermott aptly tells the story of Gary Lynch and his twenty year effort to understand the biochemical process and brain functions that support human memory. But wait - there is more. McDermott tells the story in a very compelling way, he explains the science in easy to understand terms, and describes the primary characters very well. If you have an interest in neurosocience, this is a good, non-technical book. Readers will gain insight into memory and better understand how the research contributes to that understanding.

In sum, this is an informative, well written book. Stephen Hoye does his usual best in the great reading.

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10 of 10 people found this review helpful

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