A collection of 19 essays on the constitutional, moral, philosophical, and practical aspects of the U.S. government's failed War on Drugs. For Vance, the fundamental issue in drug regulation is individual rights. He does not at all deny that these drugs can cause great harm; but the issue of regulation is not to be settled by balancing the benefits and harms of open access to drugs against the benefits and harms of their regulation or prohibition. Vance, it is apparent, has launched a remarkable war of his own, conducted with superb generalship, against the drug war; and one of the arguments in his campaign strikes me as an especially effective one. The harms of tobacco and alcohol vastly exceed the ill effects of dangerous drugs, yet there is no call to ban them. Prohibition is recognized by nearly everyone as a failure, not to be repeated. If this is so, how can one justify banning less dangerous substances? Vance writes from a viewpoint that will surprise many readers.